三、各學(xué)校研究重點(diǎn)
:
1.IUB:注重蛋白與核酸的各種分析研究。
Faculty-47人
·Protein-protein and protein-ligand interactions 蛋白質(zhì)間、蛋白質(zhì)-配基交互作用
·Macromolecular structure determination大分子結(jié)構(gòu)測定
·using NMR and X-ray crystallography (使用磁核共振和x射線晶體學(xué)分析法)
·Lipid and membrane biochemistry 脂類與膜生物化學(xué)
·DNA synthesis and repair DNA合成與修復(fù)
·Signal reception and transduction 信號(hào)接收與傳導(dǎo)
·RNA structure and function RNA結(jié)構(gòu)與功能
·Transcription initiation and termination 磷酸化形成與終結(jié)
·Mitosis and cell cycle control 有絲分裂和細(xì)胞循環(huán)控制
·Bioorganic and bioanalytical analysis 生物有機(jī)和化分析
·Biophysical analysis and molecular trapping 生理分析和分子捕獲
2.University of Houston:亞細(xì)胞和高分子層面上的生化反應(yīng),包括多個(gè)領(lǐng)域和多種研究方法:
Faculty-15人
macromolecular structure and function as elucidated by nuclear magnetic resonance磁核共振分析大分子結(jié)構(gòu)和功能;X-ray crystallographic and spectroscopic techniquesx射線晶體學(xué)和光譜法;enzyme reaction mechanisms酶反應(yīng)機(jī)制;genomics基因組學(xué);computational methods in molecular biology分子生物學(xué)計(jì)算方法;computational biochemistry/biophysics計(jì)算生化/生理學(xué);computer-aided drug design計(jì)算機(jī)輔助藥物設(shè)計(jì);Signal transduction信號(hào)傳導(dǎo);neurochemistry神經(jīng)化學(xué);ion channel structure and function等離子信道結(jié)構(gòu)與功能;the role of RNA in molecular evolution分子進(jìn)化中RNA功能分析;biotechnology分子工藝學(xué)。
3.Suny-SB:集中在蛋白類和膜的研究
Faculty-32人
Enzyme action酶反應(yīng)(proteinase chemistry蛋白酶, hydrolysis of neurotransmitters神經(jīng)傳遞素水解); carcinogenesis and DNA repair癌癥與DNA修復(fù); structure of membranes and their components 膜結(jié)構(gòu)與組成(proteins蛋白質(zhì), lipids脂類, glycoproteins糖蛋白類, caveolae細(xì)胞質(zhì)膜微囊); carbohydrate biochemistry碳水化合物; second messenger signaling and signal transduction第二信號(hào)傳遞與信號(hào)傳導(dǎo); growth factors細(xì)胞因子; drug design藥物設(shè)計(jì); the structure of ion channels等離子信道結(jié)構(gòu); mouse development白鼠研發(fā); protein folding蛋白折疊; mammalian fertilization哺乳動(dòng)物授精; yeast geneics酵母基因; 和biomolecular modeling分子建模。
4.Osu:應(yīng)用性強(qiáng),尤其偏工科。
Faculty-17人
Organelle biogenesis in green plants綠色植物細(xì)胞器官生源論:表達(dá)與機(jī)制;protein conformation and function蛋白質(zhì)形成與功能;metal based catalysts and sensors金屬催化劑和傳感器;Protein engineering蛋白質(zhì)工程;Protein and nucleic acid structure and dynamics蛋白質(zhì)與核酸結(jié)構(gòu)與動(dòng)力;protein-protein interactions蛋白質(zhì)間反應(yīng);molecular recognition分子識(shí)別;signal transduction信號(hào)傳導(dǎo); enzyme catalysis酶催化劑;computational methods計(jì)算方法;NMR methodology核磁共振法;coenzymes輔酶
5.UIUC:應(yīng)用性很強(qiáng),在轉(zhuǎn)換、機(jī)制反應(yīng)等方面是重點(diǎn)。
Faculty-34人
Molecular structures分子機(jī)構(gòu), conformational changes構(gòu)成變化, thermodynamic stabilities and functions of nucleic acids熱力學(xué)穩(wěn)定性和核酸功能;protein/nucleic acid complexes蛋白質(zhì)/核酸綜合;Structure/function relationships in photosynthetic energy conversion光合能源轉(zhuǎn)換機(jī)構(gòu)/功能關(guān)系; structure of membrane proteins, mechanism of energy conservation膜蛋白結(jié)構(gòu)與能量保存機(jī)制; Genetic approaches to regulation of lipid metabolism脂類新陳代謝的基因調(diào)節(jié); protein-lipid interaction蛋白-脂類交互反應(yīng); Mechanisms of Enzyme-Catalyzed Reactions and Functional Genomics酶催化反應(yīng)與功能性基因組織機(jī)制;Protein design and its application in biotechnological application蛋白質(zhì)設(shè)計(jì)與生物技術(shù)應(yīng)用;Structural and mechanistic study of DNA and RNA enzymes and its application in pharmaceutical applications核酸結(jié)構(gòu)與機(jī)制研究和其藥物應(yīng)用;biological energy conversion生物能量轉(zhuǎn)換; molecular engineering of ligand-protein interactions 配基-蛋白交互作用的分子工程學(xué)。